The way I understand those two exclusions, is that for your case I would have used the global exclusion for the statement of never taken any vaccine (regardless of what the disease the vaccine is for) and the specific exclusion to rule out the individual has never taken any vaccines against, say Covid-19. As per now you’ll have to use the ‘Medication’ category, while it can be discussed to add a ‘Global exclusion of vaccination’ RTNC or Coded text alternative in the future (see below).
However, there are change requests to both archetypes, which will most likely result in a major redesign. One is to change from EVALUATION to OBSERVATION, among others are changing from Runtime Name Constraint (RNTC) to Coded text for the elements where there are RTNC.